Summary
1. Rough ER and smooth ER;
2. Signal hypothesis, translocation into ER;
3. Single-span and multi-span membrane proteins;
4. Glycosylation;
5. Protein folding;
6. Lipid synthesis
Transport through the Golgi may occur by vesiculartransport or cisternal maturation
Summary
1. Vesicular transport, biosynthetic-secretory and endocytic pathways;
2. Coated vesicles;
3. Coat assembly and disassembly, budding, dynamin, coat-recruitment GTPases;
4. Targeting and fusion by Rab GTPases, SNAREs;
5. ER to Golgi: COPII, folding, fusion (cluster), retrograde;
6. Golgi apparatus structure and polarity;
7. Continuation of glycosylation;
8. Compartmentalization of Golgi cisternae;
9. By now we have introduced gated transport, transmembrane transport and vesicular transport.
